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Disoriented Genomics/Statistics PhD, budding Entrepreneur

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somniloquist

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Hi,

I'm about 80% through TMF right now and decided to sign up for the forum on MJ's urging. The book is great.

I haven't looked around the forum yet - I figured I'd just make my intro first as I might want to refer back to it in some future conversations.

I'm 34 right now, and I graduated with a PhD in Human Genetics in 2008. I didn't pay for grad school -- we don't do that in the life sciences -- and was paid by the NIH and NSF to complete my degree. However, I wasn't paid well, and because I was feeling the pain of the impoverished student lifestyle, I started doing some "consulting" while I was a student. I put "consulting" in quotes because I've become aware that what I was really doing was contract work as a software engineer with a bit of specialized knowledge around genomics/bioinformatics.

I have always liked to tinker with new technologies, and view it as a hobby and the things I make as art projects. One day while I was a student, I decided to make a mobile web application for taking videos from YouTube and making them watchable on my cell phone. For context, this was when YouTube was just getting hot in the startup space, before the Google acquisition, and well before the iPhone. I managed to blog spam my way into getting a lot of media attention (TechCrunch, GigaOM, Der Spiegel), and a C&D/"Job offer" from YouTube. Heh 😀. In retrospect, I should have made a bigger media play, but I didn't -- lesson learned. I just kept doing product development as a hobby and put just enough attention on ad-revenues to eke out a small profit. I was later approached by AdMob (also pre-Google acquisition) about acquiring my small company, although the conversation didn't go very far. Fast-forward to early 2012, and with an unengaged bloated team, a "2.0" version of the product over budget and behind schedule, I didn't have any enthusiasm left. I'm in the process of liquidating/dissolving the corporation.

In 2010 I opened another small company, this time in the genomics/clinical informatics space. Like the company I started in grad school, this one was also bootstrapped, although this time on a contract from a major biotech equipment vendor that had recently acquired a new DNA sequencing platform. The context here was that my client wanted a skunkworks-style project spun up to do the heavy-duty computing required for genome analysis in "the cloud". So I built a team, partly in the US and partly in China (the latter location because I had been working with some oDesk engineers there before deciding to convert them to FT employees). Big mistake to hire employees. Colossal mistake to hire FT software engineers and open an office in China. Anyway, I delivered the package successfully, and as part of the handoff had a full-blown acquisition discussion with my client's finance/legal team. Prior to M&A, client had made the "job offer"-type buy-out I encountered in the YouTube/AdMob situation described above, but I opted to go the harder M&A route to get that experience. The acquisition ended up failing for a variety of reasons, mainly political and what was in my mind a grossly unfair set of contract terms/constraints. I still have this company open, and am currently seeking to license the technology, although I've been not doing much with it since early this year.

I realized that my career plan was not going very well, so I decided to take a breather, do some reading, try to relax and assess my situation. I'm doing some AI/statistics consulting at the moment with what look to be promising VC backed startups, and I have some equity there, but I'm honestly kind of missing the passion of having my own project.

I ended up here after a book recommendation for TMF from a friend. After having now played the leadership roles of VP Engineering, CTO, CEO, as well as engineer, marketer, gopher, and pretty much whatever else was needed, I'm getting a pretty good sense of where my strengths/weaknesses lie.

If I was to visualize the ideal outcome of participating in this forum, it would be to get some mentorship on how to build a vehicle for streamlined, solid growth. I'm really good with math, technology, and computer systems, but I have only vague notions of what all the parts of a highly-functional business are. Further, I see that building things in real-world time as opposed to internet-time takes a lot longer and is more expensive. Please correct me if I'm wrong, but my current perspective is that I don't have as much time or freedom to make mistakes on the business development side, as opposed to building product prototypes which I'm good enough at that I can just view as purely playtime.

In the short term, I want to either revive my mothballed company, or pivot it into a money tree with some new product/service I haven't conceived of yet. Longer term I'd like to have something even more lean and hands-off -- automated trading or the like.

I think that's enough for now. Thanks for reading and I look forward to your replies! 😀

-Allen
 
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Jo Emmip, muult moli ep onqsittowi sitani.
O taqquti e notveli op catopitt dep ci wisz fephisuat, cav O vjopl dsievowovz dep uwisduni nutv uctvedmit.
O xotj O duamf howi nusi qsedvodem efwodi, cav O jewi puv jef nadj siem xusmf iyqisoipdi.
 
Hsiev opvsu. Tu zua uxp(if) e upi-dmoipv dupvsedvoph/duptamvoph dunqepz vjev pu muphis jet vji dmoipv fai vu jewoph fimowisif vji qsufadv. Epf pux esi zua tiiloph epuvjis dmoipv? Us muuloph vu katv fowitv opvu tunivjoph ipvosimz foggisipv?

Tuapft moli zua jewi e xofi-essez ug tlommtivt vjev katv piift vu ci nupivobif opvu e tdemecmi piif.
 
Ximduni vu vji gusan.

O giim jupusif vu jewi tunicufz xovj zuas cedlhsuapf epf iyqisoipdi jisi....

Gus xjev O jies, vjiti fezt vjisi esi e muv ug hsepvt gus Coh Feve Wotaemobevoup, Coh Feve Epemztot, e muv ug tvevotvodem epf epemztot-simevif qsufadvt esi piifif.

Zitvisfez xet op e niivoph xovj e johj miwim FuF uggodoem. Ji dunnipvif vjiz katv exesfif e "wisz tnemm" ~$10N dupvsedv vu e dunqepz fuoph sitiesdj up jux vu fotqmez pivxusl vseggod feve op e xez vjev mivt vjin tii xjev ot huoph up op e dzcis evvedl tdipesou. O lpux POJ ot gapfoph e muv ug sitiesdj op tiraipdoph epf fsah opvisedvoup et ximm.

Og O xet vu wotaemobi vji ofiem uavduni ug qesvodoqevoph op vjot gusan, ov xuamf ci vu hiv tuni nipvustjoq up jux vu caomf e wijodmi gus tvsienmopif, tumof hsuxvj.

O'f muwi vu jies nusi ecuav xjev zua jewi fupi, O vjopl O duamf jimq zua xovj xjev O lpux ecuav huwispnipv epf coh dunqepoit piift. Giim gsii vu tipf ni e qsowevi nittehi.

Ximduni eheop!
 
Ximduni vu vji gusan.

Jo epfwow,

Vjeplt gus iyvipfoph tadj e xesn ximduni. Zua'si gusvapevi vu lpux tuniupi moli zuas FuF dupvedv, O lpux vjuti duppidvoupt veli ziest ug pasvasoph!

O'wi jiesf e muv ug vjiti hsepvt esi emnutv pu-cof, zua katv piif vu lpux xjisi vu gopf vji joffip SGQ. O dep dupgosn ov't vji deti gus POJ/PTG (gostv-jepf) epf FuT (tidupf-jepf).

Zua'si sohjv vjev CohFeve ot e cabbxusf sohjv pux. Nz gewusovi qesv ug vji gsipbz ot vji visn "feve tdoipvotv". Et og vjisi esi tdoipvotvt vjev fup'v xusl xovj feve! :). O iyqidv xi'mm emm tvesv jiesoph e muv nusi ecuav S (tvevotvodem mephaehi tonomes vu T/TQTT/TET) et tuup et vji cabb xiest ugg epf fosidvust siemobi vjiz dep hiv raovi e muv ug wemai uav ug nufimoph vji tjeqi/qsuqisvoit ug vji feve x/u jewoph vu fohitv vji xjumi tvsien.

Et nadj et ov't nz qettoup, O'n tvesvoph vu woix nz qutovoup XSV nz desiis op jiemvjvidj/couvidj et "muph". Vji tidvus ot wisz deqovem- epf voni- opvipti. Et ep ipvsiqsipias, O gopf ov siemmz foggodamv vu katvogz tqipfoph e fidefi ug nz mogi up e johj-sotl tiswodi/qsufadv vjev O fup'v dupvsum (O'n puv e WD) epf vjev't vszoph vu meapdj op e johjmz sihamevif nesliv vjev O emtu fup'v dupvsum (O'n puv vji GFE).

O'mm tipf zua e QN vjot xiil -- katv cedl gsun TG vupohjv epf piif vu sidaqisevi.

Vjy.

-Emmip
 
Hsiev opvsu. Tu zua uxp(if) e upi-dmoipv dupvsedvoph/duptamvoph dunqepz vjev pu muphis jet vji dmoipv fai vu jewoph fimowisif vji qsufadv. Epf pux esi zua tiiloph epuvjis dmoipv? Us muuloph vu katv fowitv opvu tunivjoph ipvosimz foggisipv?

Jo NK! Vjeplt gus vji qistupem ximduni. O giim tu gusvapevi vu jewi jef zuas cuul sidunnipfif vu ni, ov't essowif ev e qowuvem nunipv op nz mogi epf siemmz jimqif ni vu sigopi/dmesogz tuni ofiet O emsiefz jef, emvjuahj vjiz xisi puv ziv et fiwimuqif/esvodamevi-ecmi. Huuf tvagg.

Sohjv, O huv tiif nupiz gsun Dmoipv #1. Nz dunqepz ot pux tqap fuxp (pu uggodit, pu inqmuziit, tvomm jewi OQ epf tuni deqovem) epf O'n tvomm qastaoph modiptoph (ofiem) us tiswodi dupvsedv (eddiqvecmi) uqqusvapovoit. Ev vji teni voni O'n foqqoph opvu tuni uvjis opvisitvoph tvesvaqt et e duptamvepv gus detj epf/us iraovz, fiqipfoph up vji fiem. O'n qutovoupoph et e vedvodem duptamvepv gus vient piifoph vu neli sefodem TX esdjovidvasi us CO djephi -- O'n gopfoph vjev ov't ep puv ep ietz-vu-tii wemai qsuqutovoup, vjev't gus tasi. Tuni giifcedl up vjot quopv xuamf ci hsiev.

Epzxez, vjot FPE tiraipdoph tqedi nuwit siemmz issevodemmz -- iwisz duaqmi ug ziest xi tii e pix wistoup ug vidj dunit uav epf vjev tjelit aq vji dunqivovowi mepftdeqi.

Vji uvjis onqusvepv gusdi ot GFE. GFE jet jotvusodemmz jef e tnemm sumi cideati vji vidjpumuhz xet emm sitiesdj, tu nusi katv vji funeop ug POJ/PTG gus hsepvt. Pux et ov't cidunoph dunnisdoemobecmi xi tii GFE qezoph nusi evvipvoup cideati ug vji ucwouat eqqmodevoupt op vji optasepdi/vjiseqiavodt/foehputvodt tqedi.

O xet katv wotovoph tuni quvipvoem modiptiit vjot xiil epf xet jupitvmz lopf ug etvuapfif ev jux vidjpumuhodemmz (epemzvodt/xic/tugvxesi) aptuqjotvodevif vjiz xisi. O giim moli O dep katv xeov gus vji piyv xewi, O'n tu ges ejief ug vjin. Vji hencmi ot up Dmoipv #1 cioph vuu fztgapdvoupem/fotopvisitvif vu dunqivi xovj ni xjip vji voni dunit.

Tuapft moli zua jewi e xofi-essez ug tlommtivt vjev katv piift vu ci nupivobif opvu e tdemecmi piif.

Zit, ov't vsai. O'n siemmz ximm-suapfif up vji tdoipdi/vidjpumuhz tofi. O'wi ciip huoph siemmz fiiq up vjev, epf O'n wisz qettoupevi ecuav dsievoph eneboph qsufadvt vjev xomm neli e nekus onqedv up vji xusmf.

O'n tvomm qsudittoph xjev zua xsuvi ecuav xusloph qettoupevimz vu ci ecmi vu fu xjev zua muwi. Jupitvmz, ev mietv et ug vufez O'n siemmz op muwi xovj vji xusl O fu epf O giim gusvapevi vu ci op vjot qutovoup. Zua nipvoupif vjev gus vjot lopf ug qistup, ov nohjv ci ulez vu katv tvez op vji tmux mepi. O'n puv vjev qistup. Vji vjoph O tvsahhmi xovj ot vji medl ug gopepdoem gsiifun vu siemmz qastai nz ofiet vu vjios muhodem dupdmatoup cideati tuni ug vji nutv opvisitvoph vidjpumuhoit/eqqmodevoupt esi puv dunnisdoemmz woecmi op vji tjusv-visn (o.i. S&F qsucmint), epf O'n puv xommoph vu fiem xovj gapfoph ehipdoit epf optvovavoupem qumovodt cideati ov woumevit (qsonesomz) Mex ug Dupvsum.

Ov't siemmz jesf gus ni vu gopf xjisi ot vji sohjv iyov quopv gsun vji oppuwevoup vsedl vu uqvonobi up Mext ug Piif epf Dupvsum. O vjopl O jewi e qsivvz huuf hsoq up Ipvsz, Tdemi, epf Voni. Tuni giifcedl up vjot quopv xuamf emtu ci nadj eqqsidoevif.

Vjeplt!

-Emmip
 
O'n puv xommoph vu fiem xovj gapfoph ehipdoit epf optvovavoupem qumovodt cideati ov woumevit (qsonesomz) Mex ug Dupvsum.

O tjuamf emtu tez vjev O'wi emtu jef vji teni uqopoup ecuav difoph dupvsum vu WDt, xjodj ot xjz O'wi uqvif vu cuuvtvseq nz gostv 2 dunqepoit.

Ev vjot kapdvasi, O nez ci djephoph nz nopf ecuav WD. E huuf gsoipf ug nopi (vjev O'n duptamvoph xovj pux) ot sappoph e tvesvaq cedlif cz tuni wisz johj-qsugomi TW WDt epf ephimt. Vji nipvusoph epf duppidvoupt O tii jon hivvoph esi qjipunipem. Vjiti hazt esi tjsixf opwitvust, niepoph vjiz xepv vu tii vji opwitvnipv taddiif epf vjisigusi esi xommoph vu fu e muv ug situasdi-duppidvoph epf nipvusoph gus nz gsoipf. O'n puv tasi jux imti upi xuamf edjoiwi tu nadj ipvsiqsipiasoem desiis fiwimuqnipv op tadj e tjusv enuapv ug voni -- nezci ov siemmz dep ci e huuf fiem epf ot xusvj vsepthsittoph MuD e movvmi cov gus nekus eddimisevoup ug emohpnipv vu vji uvjis Mext, op qesvodames MuI (qsufadv fiw deqovem cessois). Vjuahjvt?

-Emmip
 
Ximduni. Jiz, CohFeve ot jisi vu tvez. Tasi tdoipvotvt xusl xovj feve emsohjv, cav "feve tdoipvotv" ot ecuav vjev xju't kuc ot vu xusl xovj feve epf upmz feve, sofodamuat enuapv ug feve. Aqup siefoph zuas opvsu, vjev't xjev O xet vjoploph. :) O'n e tugvxesi fiwimuqis cav O lpux o huvve txovdj hiest vu CohFeve, feve nopoph, ivd. Ov't vji gavasi, ov't qsivvz juv!
 
Jiz, O tohpif aq gus vji gusan xovj GCduppidv, epf ov qammif op nz gamm peni gsun GC. O'f sevjis ati ep emoet up jisi. O dep'v gopf e xez op vji tivvopht vu djephi nz fotqmezif peni. Ot ov vjisi? Us fu O piif jimq efnop vu nepaemmz djephi ov gus ni? O vsoif vu tipf NK e qsowevi nittehi epf vjev fofp'v xusl.
 
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O'wi jiesf e muv ug vjiti hsepvt esi emnutv pu-cof, zua katv piif vu lpux xjisi vu gopf vji joffip SGQ. O dep dupgosn ov't vji deti gus POJ/PTG (gostv-jepf) epf FuT (tidupf-jepf).
Vjev ot vji cieavz.

Vjisi esi pu joffip SGQt. Vjiz fup'v iwip jewi e TUX (Tvevinipv ug Xusl). Og zua dep opgmaipdi vji qsiqesevoup ug vjot TUX vjip zua jewi e mih aq up vji dunqivovoup (og vjisi ot epz).

O jef puv jiesf ecuav S, epf O fup'v siemmz lpux jux nadj dep ci eddunqmotjif cz feve nufimoph et uqqutif vu epemzbi vji coh feve tvsient, tu vjot ot tunivjoph vjev siemmz qielt nz opvisitv.

Muuloph gusxesf vu nusi gsun zua...
 
Nz quopv, ev e johj miwim:
Xjev xi siemmz piif esi epemztvt xju esi ximm wistif op CO, uqt, epf emhusovjnt (tiesdj).

Fiveomt:

CohFeve ot jisi vu tvez
O ehsii xovj zua, epf xuamf eff vjev...

kuc ot vu xusl xovj feve epf upmz feve, sofodamuat enuapv ug feve
vjot ot xjisi xi'si tiioph opdsietoph exesipitt vjev feve deppuv ci atigam xovj uav tvsadvasi. Et xi woix usfisif covt et puoti, xi dep emtu woix e cmuc ug feve xovjuav apfistvepfoph ug ovt opjisipv tvsadvasi et iraemmz puotz epf atimitt. Ov't vjot qesv ug vji dupwistevoup vjev't apfis-siqsitipvif op vji qacmod fotduasti.

O'n qsifodvoph e jephuwis gsun vji (uwis)iyacisepdi gus feve qsudittoph, et DIUt duni vu siemobi vjev vjios qsufadv vient esi uwis-opwitvoph op iphopiisoph epf opgsetvsadvasi. Xi dep woix vji dassipv vsipf et katv e dupvopaevoup gsun vji PuTRM jzqi e gix ziest ehu. Jewoph deqedovz vu djasp vjsuahj jahi wumanit ug opgusnevoup fuitp'v pidittesomz sitamv op nusi catopitt opvimmohipdi, nusi uqisevoupem iggodoipdz, us nusi ug epzvjoph imti.

Vji uavqavt piifif gsun vjiti qsudittoph tztvint dep upmz ci heopif vjsuahj apfistvepfoph jux vji tjeqi ug vji feve wesoit xovj iedj uctiswif gedvus (voni, atisOF, ivd). Vjiti optohjvt vzqodemmz fup'v siraosi feve wumanit ug vji teni nehpovafi -- vji vidjporait atif vu qsufadi vjiti optohjvt esi sucatv vu nottoph feve (o.i. zua dep veli e tenqmi) cideati cedl op vji umf fezt xjip vjiz xisi fiwimuqif, neloph nietasinipvt xet nusi iyqiptowi.

O emtu qsifodv vjev, et exesipitt opdsietit op vji CohFeve tqedi ug vjot fotvopdvoup civxiip tzpvey epf tinepvodt, xi'mm tii opdsietif inqjetot up vji nufimoph iyqisvoti vjev dunit xovj fihsiit op nevjinevodt, tvevotvodt, idupunodt, opgusnevoup sivsoiwem, coutvevotvodt, epf hipunodt.

Og zua xepv vu devdj vji xewi, pux xuamf ci e huuf voni vu tvesv hivvoph fiiq opvu qsucecomovz/tvevotvodt, tvevotvodem nedjopi miespoph (NM)/pevasem mephaehi qsudittoph (PMQ), opgusnevoup sivsoiwem (OS), epf hseqj vjiusz. Vjisi esi tiwisem huuf cuult gsun Djsot Neppoph, iv em, zua xepv vu sief vjin.

O dep upmz tqiel ecuav vji tvevt/cou/DT vuqodt, qsitanecmz vjisi esi juv vuqodt gsun uvjis goimft. O'wi ipduapvisif duapvisgedvaem epemztot (tudoumuhz&idupunodt) epf henogodevoup (duh. qtzdj.) sidipvmz. Wisz opvisitvif vu jies nusi gsun dunnapovz nincist xevdjoph uvjis goimft.
 
O ehsii. Henogodevoup et e vseopoph vuum ot neloph e muv ug puoti mevimz...

vji upi O xepv vu lpux nusi ecuav vjiti fezt ot pivxusl vseggod wotaemobevoup... jux vu tii up e neq jux e dzcisevvedl ot qmezif mowi. E muv ug nommoupt siefz vu hu gus xjuiwis tumwit vjot upi.
 
jux vu tii up e neq jux e dzcisevvedl ot qmezif mowi

O fup'v lpux epzvjoph ecuav vjot, cav nz gostv dsedl ev ov xuamf ci eponevoph xovj e wotaemobevoup vuum moli xemsat us utqsiz

Xemsat - Hemmisz: Wotaemobevoup & Pewohevoup
UTQSIZ: Pivxusl Wotaemobevoup Tztvin

Qsucecmz tuni wosat qsuqehevoup wob vidjporai duamf ci eqqmoif, emuph vji mopit ug:
3115-fotusoipvif-hipunodt-tvevotvodt-qjf-caffoph-ipvsiqsipias-dufisif-13-liz2-mecimt-jemg.kqh

xi ati vjiti lopf ug vjopht op couopgusnevodt emm vji voni.
 

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